Nothing significant really.
You can blend some of the oil holes, but it really isnt necessary. I use a later oil filter mount then blend those passages, match the oil pump/block, but they are usually pretty close on the 427.
Mains oil feeds will look odd, you can blend them to meet the bearing, or slot the bearing, but dont take any real material out of the main saddles.
I like a HV pump and then I restrict the oil to the rockers, but a stock pump works fine too.
Be sure to run new cam bearings and make sure the guy looks at #1 cam bearing, there are two holes to line up
I do like aftermarket oil pans though, stock oil pans dont have a baffle and you can easily accelerate a 427 hard enough to uncover the pump, and while you are in there a stock 428 CJ windage tray, still available from Ford, can keep the oil off the crank
Some gotchas, make sure you have the correct main bearing set, the earlier FEs have a smaller thrust bearing
Make sure you dont use the spacer on the cam if it has its original timing set on it, old ones used to have aspacer behind the cam gear, new cam gears have the spacer built in
The center oiler has a relief valve assembly above the rear main, I shim it very tight or slug it. You have a relief in the oil pump, its not needed / desired. Be sure you at least shim it good and tight, that spring is 45 yrs old, it'll bleed off pressure at the back of the motor
63 blocks often crack at each end top head bolt, not really a big deal, but you can have them pinned but most guys just run them. 64 blocks have additional meat there
Other than that, no different than any other FE. Mines got a bunch of miles on it at 434 inches, then I rebuilt it in 2006 and stroked/bored to 489 inches and its happy as a clam
